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NAMPT allows recycling of the NAM produced through the activities of NAD + -consuming enzymes into NAD +

Transcripts were reconstructed using StringTie (v2.1.0) based on HISAT2 (v2.1.0) alignment, and gene expression levels were calculated using RSEM (v1.2.19) and quantified as FPKM (Fragments Per Kilobase of transcript per Million mapped reads)

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Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain