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Free radicals are highly reactive particles formed in your body that can damage your cells when their numbers get too high

Overexpression of dFOXO has been shown to protect DA neurons in Drosophila Pink1 -null mutants [161], while other studies have shown that dFOXO-induced apoptosis mediates DA neuron death in Drosophila DJ-1 loss-of-function mutants [162] and dLRRK mutants [163]