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CD3+ CD8+ CTL activity within the human female reproductive tract: influence of stage of the menstrual cycle and menopause

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In human monocytes and macrophages, the inhibition of the autophagy pathway drives the formation of the NLRP3 inflammasome, while increased autophagic flux reduces the secretion of IL-1, suggesting the role of autophagy impairment in driving inflammasome activation [192]