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doi:10.1146/annurev-pathol-012513-104651 (2013)

Atractylodes macrocephala exhibits anti-hyperuricemic and anti-inflammatory properties in animal models, reducing IL-1 and TNF- levels while activating AMPK/SIRT1 signaling and suppressing NF-B-mediated macrophage polarization toward pro-inflammatory phenotypes (Qian et al., 2023)