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This review aims to summarize the role of the oxidative stress in the pathogenesis of AD, focusing in the main oxidative products (DNA, protein, and lipid oxidation products), as well as antioxidant therapeutic approaches involving natural products, nanomaterials, hydrogels, and microneedles

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TB-500 has been shown to accelerate wound healing in patients with venous ulcers by 45% [11]

15,16 However, the authors of the meta-analysis admit that it is difficult to apply these results clinically due to major differences between included studies, and the RCT only including 60 patients