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A wide array of metabolic processes, cofactors, vitamins, and minerals are integral to maintaining ocular structures such as the iris, retina, choroid, photoreceptors, lens, cornea, and vitreous humor

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Most clinical trials have used a 500 mg dose taken twice a day

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[23], these scores rely mostly on clinical comorbidities, rather than thrombogenic mechanisms such as blood stasis, hypercoagulability and endothelial dysfunctionknown as Virchows triad. In view of the above arguments, it does seem very timely to revisit these, and indeed to develop new methods of assessment based on markers of thrombotic problems including biochemical markers such as those in Table 5, more physiological methods of endothelial dysfunction such as flow-mediated dilatation [378], and, in particular, fibrinaloid microclots