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PMID 17070848

D eNOS Endothelial nitric oxide synthase ERK Extracellular signal-regulated kinase FA Fatty acyl groups FasL Factor-related apoptosis ligand FoxO1 Forkhead box transcription factor O1 GLP-1R Glucagon-like peptide 1 receptor GP Glycerophospholipids GR Glutathione reductase GSH Glutathione HID 2-Hydroxyisoflavanone dehydratase HO-1 Heme oxygenase-1 HPA Hypothalamicpituitaryadrenal IBS-D Irritable bowel syndrome IGE Immunoglobulin E IGF Insulin-like growth factor IgM Immunoglobulin IL Interleukin JNK c-Jun N-terminal kinase Keap1 Kelch-like ECH-associated protein 1 LKB1 Liver kinase B1 LPS Lipopolysaccharide LTC4 Leukotriene C4 M3 Muscarinic receptor-3 MAO Monoamine oxidase MCP Monocyte chemotactic protein MDA Malondialdehyde MMP Matrix metalloproteinase MMP-9 Matrix metalloprotein-9 mTOR Mammalian target of rapamycin

The therapeutic efficacy of Lorazepam in preserving spinal cord integrity underscores the clinical potential of targeting pH-sensing GPCRs in ischemia-reperfusion pathologies

Conversely, NRF2 knockout reduces GSH levels thus enhances ferroptotic sensitivity (Tang D

& Rasmi, R