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Pressure to or stimulation of these points induces the release of endorphins, serotonin and other neurotransmitters that can help relieve pain and support natural healing mechanisms

Q., Dziuba, N

The population frequency of severe early-onset CBS deficiency ranges from 1 in 60000 to 1 in 900000 between countries, and the worldwide birth frequency of clinically ascertained patients was estimated to be 1:122000 [38]