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Since accumulative evidence supports the hypothesis that the gut microbiota are involved in the progress of human syndromes such as obesity, diabetes, metabolic syndrome, cancer, cardiovascular syndrome, and neurodegenerative diseases, it is conceivable that the defense against age-related syndrome development and progression, hypothesized for some anti-senescence mixtures, is related to the properties of such molecules on the microbiota [75]

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According to Cleveland Clinic, these include: Vitamin B9 (folate) Vitamin B6 Vitamin B3 (niacin) Vitamin B1 (thiamin) Vitamin E When to See a Doctor Always check with your doctor if you're experiencing leg cramps or leg pain regularly (whether at night or during the day), to find out the cause