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Though effective treatments to halt or reverse CKD are extremely limited, regulating renal senescence is expected to provide a new target for its intervention

Bilic M, Bumber Z, Blagaic AB, Batelja L, Seiwerth S, Sikiric P

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To further probe the catalytic mechanism of arGSTs, we conducted quantum mechanics/molecular mechanics (QM/MM) calculations based on the ternary complex of GSH, ()-catechin ( 12 ) and Pt GSTF8