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References Froese, D

We know now that the role of TBK1 in regulating selective autophagy is much broader than previously thought with recent studies implicating TBK1 in the direct recruitment of cargo receptors as well as the early autophagic machinery to intracellular bacteria and mitochondria, which will be described in more detail below (99)

doi: 10.1101/cshperspect.a029082 192 SabatinoJ

Shaking creates aggressive mechanical forces that can break the delicate peptide bonds and denature the molecule, rendering it inactive

Sheep and cattle with low levels of selenium or at risk of clinical deficiency should be treated with a suitable long-acting therapy, such as Selovin LA from Elanco