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[10] found some 1-methylquinolinium scaffolds modified with primary amine substitutions displaying both high passive membrane diffusion in PAMPA and high active transport membrane permeability in a bidirectional permeability assay with Caco-2 cells, and one of them (5-amino-1-methylquinolinium (5-amino-1MQ)) has significant effectiveness against diet-induced obesity

Nat Rev Clin Oncol 14(1):1131 Martnez-Reyes I, Chandel NS (2020) Mitochondrial TCA cycle metabolites control physiology and disease

reuteri isolated from the feces of a healthy weaned piglet decreased the intestinal permeability to dextran in ETEC K88-infected IPEC-1 but had no effect when used alone

Trends Biochem Sci 2021;46:329343

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