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10.3390/ijms22168738 31 DuanZ.ChenY.YeM.XiaoL.ChenY.CaoY.et al (2022)

Methylation changes in aging are linked to neurodegenerative diseases, such as AD, where demethylation of neural function-regulating genes, such as APP , may lead to -amyloid accumulation (Jung and Pfeifer, 2015)