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The metabolic kynurenic pathways is likely also implicated in ME/CFS, owing to common mutations in IDO2 (76) such as R248W and Y359STOP (77)

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doi:10.1016/j.mimet.2016.06.012 Yoshida H, Arai S, Hara KY, Yamada R, Ogino C, Fukuda H, Kondo A (2011) Efficient and direct glutathione production from raw starch using engineered Saccharomyces cerevisiae