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Measurements of a variety of observable properties can be used to identify particular materials

Among these, riluzole (2-amino-6-trifluoromethoxy benzothiazole) is a neuroprotective drug approved for use in amyotrophic lateral sclerosis (Miller et al., 2002), which appears to act through decreasing glutamate release by stabilizing inactive Na + voltage-gated channels, shifting voltage dependence of the channel in the hyperpolarizing direction (Herbert et al., 1990)

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As part of the Pediatric Preclinical Testing Program (PPTP), 2 astrocytoma cell lines were generated, BT-35 cells which had 2 to 5 copies of wild-type (WT) BRAF and BT-40 cells which had 5 copies of activated BRAF V600E [ ( Table 2 )]

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