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This finding correlates with those described by Kumar et al., who demonstrated that ER is crucial to enhance OLs production, myelin protein synthesis, remyelination, and axon conduction in EAE mice through the activation of the PI3K/Akt/mTOR signaling pathway, without disturbing inflammation in the corpus callosum or spinal cord (Kumar et al., 2013

Khorashad JS, Rizzo S, Tonks A

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Mecobalamin restores end-plate potential early induction by increasing nerve fiber excitability in the crushed sciatic nerve

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