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Differential effect of covalent protein modification and glutathione depletion on the transcriptional response of Nrf2 and NF-B

A molecular classifier trained on histologic rejection vs no rejection in biopsies predicted molecular rejection with AUC=0.87 but histologic rejection less well (AUC=0.65, Fig1E)

doi: 10.1007/BF01900187 51 ShambergerRJFrostDV

While not a permanent fix for most concerns, the results from PRP therapy can last for several months

Studies in primary endothelial cells grown in culture, as well as in animal models illustrate that a deficiency of GPx1 alters endothelial dependent vasodilation by regulating bioavailable nitric oxide [39, 60, 61, 70, 71]