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They also demonstrated that OPMA- S -oxide is more toxic than OPMA when cell proliferation was used as an index of toxicity (IC 50 of 22 M versus 83 M)

On the other hand, trying to immobilize the same amount of aptamer on M-270 beads resulted in 54 g (3.34 nmol, 13.4% of starting aptamer amount, 223 pmol/mg bead) aptamer immobilization on the beads corresponding to 5.38 g aptamer/mg of the beads (see Supplementary Table S2 online)

Otherwise, it cannot exert its efficacy

Moreover, JS-K diminished WNT-signaling in AR-positive 22Rv1 cells

doi:10.1017/S1461145711000617 Gigante AD, Bond DJ, Lafer B, Lam RW, Young LT, Yatham LN (2012) Brain glutamate levels measured by magnetic resonance spectroscopy in patients with bipolar disorder: a meta-analysis