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Type-2 diabetes alters the basal phenotype of human macrophages and diminishes their capacity to respond, internalise, and control Mycobacterium tuberculosis

Edwinson, A

In a clinical trial involving 31 cancer patients who had solid tumors, amifostine plus chemotherapy (cisplatin and ifosfamide plus either etoposide or paclitaxel) was compared with chemotherapy alone

Blocking TDO and IDO1 to improve the efficacy of cancer immunotherapy would be complementary