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Description

These compounds target overlapping receptor systems, and combining them dramatically increases the risk of severe gastrointestinal side effects without proportional benefit

Zharkova MS, Orlov DS, Golubeva OY, Chakchir OB, Eliseev IE, Grinchuk TM, Shamova OV (2019) Application of antimicrobial peptides of the innate immune system in combination with conventional antibiotics-a novel way to combat antibiotic resistance

Despite the therapeutic potential of these strategies, several limitations and challenges remain

Patient support There are several organisations that patients can be signposted to: Acknowledgements The authors would like to thank Shiva T Radhakrishnan, clinical research fellow (IBD), Imperial College Healthcare NHS Trust, for his support and guidance in writing this article