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[37-44] MOA OF PHENOLICS IN OBESITY MANAGEMENT Phenolic compounds are able to reduce body fat and prevent its accumulation by changing the ways the body uses fats, decreasing free radicals, reducing inflammation and regulating glucose levels

Enhanced polyamine flux activation leads to elevated energy expenditure via polyamine acetylation, utilizing Acetyl-coenzyme A (acetyl-CoA) to generate acetylpolyamines (Jackson et al., 2003)

FOXO3 also prevents pro-apoptotic BAX translocation to the mitochondria, hence protecting cells from apoptosis 100

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