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Clinical study data from published literature were collected with the semi-automated tool WebPlotDigitizer (Version 4.6, Ankit Rohatgi, Pacifica, CA, United States)

On the other hand, inhibition of GSH synthesis with BSO, independently of the cysteine pool, has been repeatedly described to induce ferroptosis ( via depletion of mitochondrial GSH pool leading to the release of cytochrome c, when combined with chemotherapy in breast cancer and leukemia, respectively (71, 72)

De Petrocellis et al., 2011)

doi: 10.1016/j.jcv.2017.12.015 44 FinanR

Natural flavonoids disrupt bacterial iron homeostasis to potentiate colistin efficacy