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As the disease advances, ferroptosis-induced release of damage-associated molecular patterns (DAMPs), exosomal transmission, and immune evasion mechanisms further amplify neuroinflammation and cell damage, establishing a cascade of intercellular pathological propagation that accelerates neurodegeneration

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Due to hemolysis of red blood cells during sample collection, one subject was excluded from all analyses ( N = 12 final subjects)

[DOI] [PubMed] [Google Scholar] 24.Rumack BH