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A phase II randomized clinical trial using aglycone isoflavones to treat patients with localized prostate cancer in the pre-surgical period prior to radical prostatectomy

Defects in RNA metabolism also have essential roles in the childhood-onset motor neuron disease spinal muscular atrophy (SMA) caused by deficiency of the SMN protein 17

For instance, the anti-CD47 antibody magrolimab has been tested in ovarian cancer patients in phase I trial yet no robust phase II/III data are presented [177, 178]

Less commonly reported reactions in the same trial included flatulence (3 to 4%), abdominal distension (3 to 4%), dizziness (4 to 5%), and low blood pressure (1 to 2%)

Nov 27 2020;30(12):2159-2170