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In the CCI model, cuminaldehyde not only alleviated allodynia and hyperalgesia at doses ranging from 25 to 100 mg/kg, but it also significantly decreased serum levels of the inflammatory cytokines TNF- and IL-1 (Koohsari et al., 2020)

In sensitive genotype, K + decreased, and Na + and Na + /K + significantly increased compared to control under salt concentrations of 90 mM and 120 mM (Masarmi et al., 2023)

doi: 10.1038/S41598-024-73326-7 12

This tissue-specific activity adds to the peptides utility in targeted research uses where specific effects on specific tissue types are desired

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