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doi: 10.1038/nature20791 279 Martinez-OutschoornUELinZWhitaker-MenezesDHowellALisantiMPSotgiaF

Key readout endpoints include serum ALT and AST enzyme release (hepatocyte membrane integrity), hepatic malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) as lipid peroxidation markers, H&E-stained hepatic necrosis area scoring (zones IIII centrilobular pattern), TUNEL-positive hepatocyte apoptosis count, and MPO activity as a proxy for neutrophil infiltration

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Int J Biol Macromol 106:12971306 Liberal , Cardoso RVC, Heleno SA, Fernandes , Barros L, Martins A (2023) Phenolic acids from fungi

However, vitamin B12 is also one of the major vitamins our bodies can't produce naturally