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They primarily exist as dimers, though some occur as trimers or tetramers

In vitro , high iron level have been shown to directly stimulate the proliferation of human lung fibroblasts and enhance the secretion of ECM and pro-inflammatory factors (107)

Targeting specific molecular pathways in reactive astrocytes presents additional therapeutic opportunities

226 Common sleep disorders, which frequently co-occur, include: Chronic insomnia (lasting three months or longer) is estimated to affect about 10% of the population

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