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The Envision 2104 Multilabel plate reader (PerkinElmer) was used for measuring the fluorescence at 540 nm excitation/590 nm emission

Unrepaired 8-oxo-G is potentially one of the most mutagenic lesions, since it pairs with A, inducing G T transversions 40 , and represents a prominent candidate to be a marker of ROS-induced mutagenesis and tumorigenesis 41