[DOI] [PMC free article] [PubMed] [Google Scholar] 11.Serra V., Salvatori G., Pastorelli G
In some embodiments, the total concentration of one or more agents encompassed by the invention (e.g., siRNA molecules) in the formulation that are sufficiently complementary to the mRNA transcript of the at least one biomarker described herein is from about 0.001mg/ml to about 100mg/ml, from about 0.01mg/ml to about 10mg/ml, or from about 0.1mg/ml to about 20 mg/ml
Gu and colleagues synthesized trimethylated CS-coated flexible liposomes (TMC-Lipo) designed for topical drug delivery and loaded with resveratrol
The included studies were conducted on healthy individuals, (Reference Naderifar, Gangeh, Mehri and Kazemi33,Reference Venkatakrishnan, Chiu and Cheng41,Reference Maeda-Yamamoto, Nishimura and Kitaichi43,Reference Kuo, Lin, Bernard and Liao52,Reference Sone, Kuriyama and Nakaya61,Reference Erba, Riso, Bordoni, Foti, Biagi and Testolin66Reference van het Hof, de Boer, Wiseman, Lien, Westrate and Tijburg68) patients with type 2 diabetes (T2D) and prediabetes, (Reference Bazyar, Hosseini and Saradar36,Reference Hadi, Alipour and Aghamohammadi37,Reference Spadiene, Savickiene and Ivanauskas53,Reference Liu, Huang, Huang, Chen, Chiu and Hsu55Reference Mousavi, Vafa, Neyestani, Khamseh and Hoseini57,Reference Mohammadi, Hosseinzadeh Attar and Karimi63,Reference Fukino, Ikeda, Maruyama, Aoki, Okubo and Iso65) obese and overweight individuals, (Reference Rondanelli, Gasparri and Perna32,Reference El-Elimat, Qasem and Al-Sawalha34,Reference Bagheri, Rashidlamir and Ashtary-Larky39,Reference Azizbeigi, Stannard and Atashak40,Reference Nogueira, Nogueira Neto, Klein and Sanjuliani46,Reference Suliburska, Bogdanski, Szulinska, Stepien, Pupek-Musialik and Jablecka59,Reference Bogdanski, Suliburska, Szulinska, Stepien, Pupek-Musialik and Jablecka60) athletes, (Reference Kondori, Ghaleh and Hosseini35,Reference Hadi, Pourmasoumi, Kafeshani, Karimian, Maracy and Entezari49) patients with metabolic syndrome, (Reference Basu, Betts, Mulugeta, Tong, Newman and Lyons58,Reference Basu, Du and Sanchez62) non-alcoholic fatty liver disease (NAFLD), (Reference Tabatabaee, Alavian and Ghalichi44,Reference Hussain, Habib Ur and Akhtar48) diabetic nephropathy, (Reference Borges, Papadimitriou, Duarte, Lopes de Faria and Lopes de Faria51) chronic stable angina, (Reference Lee, Charng, Tseng and Lai50) thalassaemia major, (Reference Soeizi, Rafraf, Asghari-Jafarabadi, Ghaffari, Rezamand and Doostan45) polycystic ovary syndrome, (Reference Mombaini, Jafarirad, Husain, Haghighizadeh and Padfar47) multiple sclerosis, (Reference Benlloch, Cuerda Ballester and Drehmer38) COVID-19, (Reference Ahmad Merza Mohammad31) and older adults
Hypercalcemia, unusual bone lesions, and human T-cell leukemia-lymphoma virus in adult T-cell lymphoma
