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Chemical Design of Both a Glutathione-Sensitive Dimeric Drug Guest and a Glucose-Derived Nanocarrier Host to Achieve Enhanced Osteosarcoma Lung Metastatic Anticancer Selectivity

10.1016/j.biopsych.2015.04.005 67 MandalP

10.1016/0167-4838(95)00141-G Biochim

Fecal matter from metformin-treated mice attenuates intestinal ferroptosis induced by IIRI To investigate the role of the gut microbiota in the anti-ferroptosis effect of metformin, we established a dirty cage group by allowing mice to feed on metformin-modulated feces from the MET group

In the yeast and mammalian cytosol, the thioredoxin pathway is considered to be the major reductive pathway with the glutaredoxin/glutathione system having only a backup or auxiliary role 42,44