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Historically, most peptides have been considered ineffective when swallowed because digestive enzymes in the stomach and small intestine break down protein structures before they can be absorbed

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[99] Hepatic effects, including elevated liver enzymes, have been reported in some patients receiving ondansetron therapy

Inhibition of proliferation of human leukaemia 60 cells by methylglyoxal in vitro

Unfortunately, chemotherapy alone is often unsatisfactory, with intrinsic and acquired resistance to conventional chemotherapeutic agents and targeted drugs developing in a short period of time