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Trained immunity Trained immunity refers to the capacity of innate immune cells, particularly monocytes and macrophages, to acquire a functional memory following an initial exposure to a pathogen or stimulus

Its molecular core involves the receptor interacting serine/threonine kinase 1 (RIPK1)-receptor interacting serine/threonine kinase 3 (RIPK3)-mixed lineage kinase domain like pseudokinase (MLKL) signaling axis (119)

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10.1016/j.freeradbiomed.2013.07.039 63 LeiP.BaiT.SunY