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DA deprivation significantly caused the activation and proliferative changes of astroglial fibrillary acidic protein-positive cells in the striatum (Zhu et al., 2020)

Given that SODs are characterized as highly efficient enzymes the intracellular (cytosol - SOD1, mitochondria - SOD2) and extracellular (SOD3) balance is shifted towards the formation of H 2 O 2 , which diffuses relatively free or is receptor-mediated transported across biological membranes [9] thereby acting as an intra- and intercellular signaling molecule (Fig

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