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3,11 A central signaling molecule for this pathway is NF-B-inducing kinase (NIK), which activates and functionally cooperates with IKK to mediate p100 phosphorylation, which in turn induces p100 ubiquitination and processing

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The SNX protein family commonly features two specialized functional domains: a BAR (Bin/amphiphysin/Rvs) domain, which enables membrane curvature, and a PX (phox homology) domain, which binds to phosphoinositides

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Decreased serum levels of polyunsaturated fatty acids and folate, but not brain-derived neurotrophic factor, in childhood and adolescent females with depression