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Therefore, after active iron supplementation in iron-deficient animals, in addition to accelerated hemoglobin synthesis, symptoms related to tissue iron deficiency and decreased iron-containing enzyme activity such as growth retardation, behavioral abnormalities, and physical deficiency can be gradually corrected

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Plusieurs essais cliniques ont effectivement observ une baisse modeste de l'indice de mlanine aprs supplmentation orale, mais ces rsultats restent fragiles : chantillons rduits, htrognit des formes et des dosages, effets limits certaines zones cutanes