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Harnessing ferroptosis to transform glioblastoma therapy and surmount treatment resistance

2.2 The coexistence of CKD and sarcopenia increases the risk of adverse outcomes The coexistence of CKD and sarcopenia not only accelerates disease progression but also significantly increases the risk of adverse clinical outcomes in patients, including cardiovascular events, hospitalization rates, and all-cause mortality

TANOOKA, H

This mechanism facilitates the spread of A from platelets into the bloodstream and eventually into the brain tissue, adding to the overall amyloid accumulation (131, 135)

In another study, IGF-1 significantly upregulated the survival of human neural progenitor cells in the 6-OHDA-induced PD model [103]