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In a study that developed a model that included microfluidic channels in a type I collagen gel, HUVECs were seeded and cultured alone or with human brain vascular pericytes or human umbilical arterial smooth muscle cells embedded in the collagen scaffold [267]

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The study reported that BPC-157 did not show a direct angiogenic effect in cell cultures in the same way, but tissue model analysis showed more adequate angiogenesis during muscle and tendon healing marker evaluation

As no relevant changes in e-GST levels were observed for bovine species (see Results section), all other mammalian species were tested without considering these physiological phases