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Mol Pharmacol 77 : 317326

This phosphomimetic, S114D mutant, in NHR-49::YFP strongly favored a cytoplasmic localization, which was dramatically different from the wild-type and more so from the phospho-dead S114A mutant (Fig

Immediately after the procedure, the plaque typically becomes palpably softer, reflecting controlled collagen micro-disruption, transient tissue edema, and cytokine-mediated relaxation of the fibrotic matrix