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Oncology : Studied as a potential adjunct for reducing cancer incidence through genomic stability

Acknowledgements This study was supported by the General Fund of Natural Science Foundation of Hunan Province (2023JJ30479), the Youth Fund of Natural Science Foundation of Hunan Province (2022JJ40330), the Scientific Research Project of the Health Commission of Hunan Province (202204014468), the Research Program of Hunan Administration of Traditional Chinese Medicine (D2022082), the Key Research Project of Hunan Health Commission (c202304019331) and the Outstanding Innovative Youth Training Program of Changsha (kq2306029)

One of the drawbacks in using tissue engineering to repair, and ultimately restore and regenerate the microenvironment, is that many of the factors used to promote these processes can also facilitate tumor survival, growth and metastasis, such as is the case with factors targeting improving angiogenesis (as reviewed in Zimmerlin et al., 2013)

For example, due to the gut microbial dysbiosis, the translocation of intestinal microorganism may occur from gut to the kidney causing kidney damage (Stavropoulou et al., 2021)