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Visfatin induces human endothelial VEGF and MMP-2/9 production via MAPK and PI3K/Akt signalling pathways: novel insights into visfatin-induced angiogenesis

[2] Ghigo E, Arvat E, Muccioli G, Camanni F

10.1016/j.cell.2022.04.011 [DOI] [PMC free article] [PubMed] [Google Scholar] Welborn VV (2020)

The biological effects of acrolein are a consequence of its reactivity towards biological nucleophiles such as guanine in DNA and cysteine, lysine, histidine, and arginine residues in critical regions of nuclear factors, proteases, and other proteins

However, NRF2 controls the transcription of NQO1 and GSTP1 (51), genes that were depleted in cells that grew preferentially in the presence of LCS3