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Our analysis used mushroom powders that were initially ash-frozen with liquid N 2 and then transferred to 80 C, whereas the Kalaras et al

Abbreviations ALT: Alanine aminotransferase AST: Aspartate aminotransferase bHb: Bovine hemoglobin CAT: Catalase Cr: Chromium Cr(III): Cr trivalent Cr(VI): Cr hexavalent GD: Gestational days GSH: Glutathione GPX: Glutathione peroxidase GST: Glutathione S-transferases H 2 O 2 : Hydrogen peroxide HMy2.CIR: Human B lymphoblastoid cell line IL-1: Interleukine-1 LPO: Lipid peroxide MDA: Malondialdehyde NOX: NADPH oxidase NTP: National Toxicology Program Nqo1: NAD(P)H quinone oxidoreductase 1 OH: Radical hydroxyl RKIP: RAF kinase inhibitor protein ROS: Reactive species of oxygen TNF-: Tumor necrosis factor- 8-OHdG: 8-Hydroxy-20-deoxyguanosine References Ahmadi S, Rastegar S, Makhdoumi P, Hossini H (2016) Removal of hexavalent chromium from aqueous solution using polyaniline: modeling and optimization

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The pathological changes caused by dysregulated signal transduction are not limited to inflammatory diseases but have also been demonstrated in cancer, autoimmune diseases, and metabolic diseases

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