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(2011) Nutrient starvation elicits an acute autophagic response mediated by Ulk1 dephosphorylation and its subsequent dissociation from AMPK

This is worsened when ME/CFS patients are upright, as the baroreflex is activated (345), further promoting vasoconstriction in skeletal muscle

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Yet, another phase II clinical trial focusing on c-Abl inhibition (NCT03655236, Table 2) is ongoing, evaluating both clinical outcome and imaging-based biomarkers