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It occurs because cagrilintide slows gastric emptying and intestinal transit, the same mechanism that promotes satiety and reduces food intake

Hohenfellner K, Niessl C, Haffner D, Oh J, Okorn C, Palm K, Schlingmann KP, Wygoda S, Gahl WA (2022) Beneficial effects of starting oral cysteamine treatment in the first 2 months of life on glomerular and tubular kidney function in infantile nephropathic cystinosis

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NAPQI builds up, causing oxidative stress, mitochondrial damage, and liver cell death

Adequate selenium status is necessary for optimal glutathione peroxidase activity, and selenium deficiency can impair the functional utilization of available glutathione