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Cancer-associated cachexia - understanding the tumor macroenvironment and microenvironment to improve management

doi: 10.1038/ismej.2014.99 221 RadAHAbbasalizadehSVazifekhahSAbbasalizadehFHassanalilouTBastaniPet al

111,112 Immunomodulators, including rituximab, cyclophosphamide, interferon-alpha, and intravenous immunoglobulin, have shown mixed results

10.1192/bjp.bp.105.015263 Br

Emerging insights into the molecular and cellular pathways have unveiled potential targets for intervention, including neuroprotective agents, gene and stem cell therapies, and innovative pharmacological approaches