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Disruptions of the TrxR1 system, although not substantially impacting either the cellular redox balance or GSH pools, disrupts embryonic patterning, Nrf2 regulation, and other signaling-dependent processes [49]

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Addressing these pathways through antioxidant interventions offers potential therapeutic avenues for mitigating oxidative stress-induced inflammation in skin disorders

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For surface functionalization, freeze-dried Fe 3 O 4 powder was first redispersed in deionized water (1.0 mg mL 1 ) and sonicated (~ 100 W, 5 min in an ice bath) to ensure a uniform suspension