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We confirmed that the knockdown of Activin receptor-like kinase 5 ( ALK5 ) and Mothers against decapentaplegic homolog 2 ( SMAD2 ), two genes of the TGFb pathway, protected dopaminergic neurons from aSyn-induced toxicity

5 Rao J, Wang H, Ni M, Wang Z, Wang Z, Wei S, Liu M, Wang P, Qiu J, Zhang L, et al

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In short, we conclude that the Wnt/-catenin signaling pathway can be divided into the following steps: Wnt Fzd Dvl -catenin destruction complex dissolved -catenin enters nucleus TCF/LEF downstream gene transcription 3

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