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Early synaptic dysfunction or synaptopathy at the level of inhibitory interneurons within the entorhinal cortex and CA3 hippocampal subregion leads to hyperactivity of pyramidal cells, which appears to play a role in the progression of AD neuropathology (e.g., tauopathy) (271, 272)

Handling & Storage Considerations Lyophilized BPC-157 should be stored in a freezer (-20C or below), protected from light and moisture, until the researcher is ready to reconstitute the material for a laboratory protocol

This compound is supplied exclusively for scientific investigation and analytical laboratory use

The oral bioavailability means that subcutaneous injection is not the only viable route