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Studies of the antioxidant pools in frataxin-depleted cultured human cells have shown significant decreases in reduced glutathione along with actin stress fibre disorganization [21], but this reduction in antioxidant pools have little or no impact on the cells under basal conditions

In contrast, even modest weight loss in obese individuals following a hypocaloric diet increased circulating zinc to normal levels (89, 101, 109)

A melting curve analysis at 95.0 C was done at the end of each q PCR to ensure that the primers used are of good quality

However, this research is preliminary

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