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Mol Aspects Med 34(23):561570

B12 is helpful in maintaining healthy nerve cells and helps with the ability to focus

Mechanistically, it was shown that SLC7A11 interacts with arachidonate 12-lipoxygenase (ALOX12), and this interaction suppresses ALOX12s lipoxygenase activity to mediate polyunsaturated fatty acid (PUFA) peroxidation, thereby inhibiting ferroptosis

Carvalho Faculty of Health Sciences, University Fernando Pessoa, Porto, Portugal Mrcia Carvalho Department of Medicine, University of Udine, Udine, Italy Giulio Castelpietra Department of Mental Health, Healthcare Agency Friuli Occidentale, Pordenone, Italy Giulio Castelpietra Department of Pharmacological and Biomolecular Sciences, Universit degli Studi di Milano (University of Milan), Milan, Italy Alberico L

These findings highlight the central role of iron dyshomeostasis in the pathophysiology of ischemic stroke and suggest that targeting iron metabolism could represent a viable therapeutic strategy