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Beyond-use dating principles from the United States Pharmacopeia General Chapter treat preservative-containing solutions as having longer safe in-use windows than preservative-free ones

Mechanistically, OA-NPs@OA concurrently suppressed keratinocyte hyperproliferation via blocking the YAP-AREG pathway axis and reduced immune cell infiltration by downregulating chemokine networks, breaking the psoriatic inflammatory loop

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Dp71f and Dp71d isoforms bind in vitro to the nuclear envelope proteins lamin B1 and emerin Given that both Dp71d and Dp71f utilize the importin 2/1 system to enter the nucleus, there may be a mechanism that favors nuclear retention of Dp71d but not Dp71f